Nightingale College educates through low-, medium-, and high-fidelity simulation. High-fidelity simulation is the artificial replication of real world situation in which learners gain knowledge and skills to be able to critically think through complex scenarios in a safe and nonthreatening environment. Nightingale College provides the most realistic simulation through computer-based mannequins.

Nightingale College also provides low- and medium-fidelity simulation that prepares and trains learners for the realism of high-fidelity simulation and clinical treatment.